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Learn MoreCIViC Summary for NQO1 Gene GeneCards Summary for NQO1 Gene NQO1 (NAD (P)H Quinone Dehydrogenase 1) is a Protein Coding gene. Diseases associated with …
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Learn MoreNQO1 t o NQO 1-bioactiv atable drugs immediately follo wing IR, therefore, hypera c - tivates P ARP1 synergisti cally, whi ch in turn depletes N AD+ and A TP, inhibiting DSB
Learn MoreWe also tested the hypotheses that massive PARP1 hyperactivation reactions after IR + ß-lap led to dramatic accompanying NAD + /ATP losses that ultimately inhibit DSB repair …
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Learn MoreIn this review, we summarize the multiple functions of NQO1, its established roles in redox processes and potential roles in redox control that are currently emerging. NQO1 has …
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Learn MoreTo prevent oxidative damage to biological components, NQO1 exerts its antioxidant effect by converting quinones to hydroquinones in a 2-electron-reduction …
Learn MoreTo enhance the curative potential of NQO1 bioactivatable drugs, we developed a novel DNQ derivative termed isopentyl-deoxynyboquinone (IP-DNQ). Our study revealed that …
Learn MoreNQO1 mRNA expression positively correlated with infiltrating immune cells and checkpoint molecule levels. The single-cell analysis revealed a potential relationship between …
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